2023-04-13

This is PMAS's COMMONS Lab daily Open Notebook.

Today is 2023.04.13

Todo today

Have a look at the COMMONS research discussion forum

- https://github.com/orgs/commons-research/discussions

Doing

Metabolite annotation Audrey and Stephanie

Annotation with https://github.com/mandelbrot-project/met_annot_enhancer

https://github.com/digital-botanical-gardens-initiative/emi_anacardiaceae/tree/main

Working on the emi_batch_00001 (Anacardiaceae) we found two interesting clusters in Pseudospondias extracts

https://pubchem.ncbi.nlm.nih.gov/compound/21581584 Ohchinolide B derivatives possibly.

Melia azedarach

https://academic.oup.com/femsle/article/120/3/267/520869

Paused

Done

Notes

Mid Thesis presentation Audrey le Cabbec

  • worked on insects metabolites in Rennes (ynsect)
  • worked with P Coulerie in New Caledonia

ICOA

Analytical, Affinity and Bioactive Strategies Cosmetic valley (Tours, Blois, Rouen) Orlean area of high horticultural prod

Eclipta alba

Presence of coumestan

5 enzymatic test (COX, elastase, ROS etc.)

Q : why such difference in the raw extracts conc used for testing ? Q : can you explain the heatmap again ? Q : stats significative diff Q : how did you annotate the compounds ? Which software ? Which DB ?

C forskohlii

Coleus forskohlii

forskolin

which gave the name to the plant ?

How do you quantify forskolin iteratively ?

Conclusion

explore the coumestan biosynthetic pathway. Why exactly ?

### Perspectives and collab in UniFr

Todo tomorrow, one day ... or never

Today I learned that